Portal hypertension essay

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Portal hypertension essay

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Typical portal vein pressure is 5 to 10 millimeters of mercury abbreviated mmHg. When the pressure exceeds 5 mmHg above inferior vena cava pressure, it is characterized as portal hypertension.

The portal vein carries nutrient rich blood from the digestive system to the liver. Normally, the veins come from the stomach, intestine, spleen, and pancreas. Tell us what you need to have done now!

Portal hypertension essay

If the vessels in the liver are blocked, it is hard for the blood to flow causing high pressure in the portal system. When the pressure becomes too high, the blood backs up and finds other ways to flow back to the heart, which causes large varices swollen or knotted bodily vessels, usually veins to develop across the esophagus and stomach to bypass the blockage.

Because of this bypass, substances such as toxins that are normally removed from the blood by the liver can pass into the general circulation. The varices become fragile and can bleed easily, sometimes seriously and occasionally with fatal results.

Portal hypertension often causes the spleen to enlarge splenomegaly because the Portal hypertension essay interferes with blood flow from the spleen into the portal blood vessels. Pressure in the portal blood vessels may cause fluid from the surface of the liver and intestine to leak into the abdominal cavity producing a condition called ascites an accumulation of serous fluid in the peritoneal cavity, causing abdominal swelling.

Sonographically speaking, portal hypertension can be separated into presinusoidal and interhepatic. Presinusoidal venous hypertension often occurs in a patient with normal liver function when the portal vein and its branches are compressed before they enter the liver.

Presinusoidal portal hypertension can be further divided into extrahepatic and intrahepatic forms. Extrahepatic presinusoidal portal hypertension can be caused by either thrombosis formation of blood clots of the portal veins or of the splenic veins.

The causes of portal vein thrombosis in adults include rauma, sepsis blood or tissue infectionhepatocellular carcinoma cancer of the liver cellspancreatic carcinoma cancer of the pancreaspancreatitis inflammation of the pancreasportacaval shunts shunt between the portal vein and inferior vena cavasplenectomy removal of the spleenand hypercoagulable states excessive blood clotting.

This form of portal hypertension should be suspected in any patient that has a normal liver biopsy and any of the clinical signs of portal hypertension ascites, splenomegaly, and varices.

The intrahepatic presinusoidal portal hypertension is caused by primary biliary cirrhosis, congenital hepatic fibrosis, toxic substances, and schistosomiasis, all of which are diseases or results of diseasesaffecting the portal zones of the liver. Cirrhosis results from the healing of a liver injury caused by hepatitis, alcohol abuse, or other causes of liver damage.

Cirrhosis is a chronic progressive liver disease characterized by the replacement of healthy cells with scar tissue. The scar tissue blocks the flow of blood through the liver and slows its processing functions because it is dense enough that it increases the resistance to portal venous blood flow and obstructs hepatic venous outflow, causing portal hypertension.

Another liver disease that produces portal hypertension in the same fashion is diffuse metastatic liver disease. Altogether, the most common cause of portal hypertension is cirrhosis.

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Thrombosis is another main cause of portal hypertension but other causes of portal hypertension include blockages of the veins that carry the blood from the liver to the heart, parasitic infection called schistosomiasis, and sometimes the cause is unknown. There are many other things that can lead to portal hypertension including thrombotic diseases of the inferior vena cava and hepatic veins, constrictive pericarditis, and any other cause of right-sided heart failure.

The onset of portal hypertension may not always be associated with specific symptoms that identify what is happening to the liver. If there is liver disease that leads to cirrhosis, the chances of developing portal hypertension is high.

The main symptoms and complications of portal hypertension include gastrointestinal bleeding black, tarry stools or blood in the stools; vomiting of bloodascites, encephalopathy confusion and forgetfulnessand reduced levels of platelets or decreased white blood cell count.

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Usually doctors make the diagnosis of portal hypertension based on the presence of ascites or of dilated veins or varices as seen on physical exam of the abdomen or the anus.

Portal hypertension can also be diagnosed by endoscopic examination, X-ray studies, ultrasonography, and lab tests.A review of the cirrhotic and non-cirrhotic causes of hyperammonemia that may be encountered in the emergency department.

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Portal hypertension is abnormally high blood pressure in the portal vein (the large vein that brings blood from the intestine to the liver) and its branches. Thomas LaVeist, keynote, speaker, researcher, professor, scientist, health policy.

Hypertension or high blood pressure can lead to heart disease, stroke, and death and is a major global health concern. A range of risk factors may increase the chances of a person developing. Portal hypertension occurs when there is an obstruction of blood flow through the liver and pressure rises within the portal vein.

This obstruction can be intrahepatic (intra=within +hepatic=liver), pre-hepatic (pre=before) or post- hepatic (post=after). Intrahepatic causes of portal hypertension. High strength clamping.

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